Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data 001    334449 005    20180522074312.AM 008    180522s |||||||||b ||00||| 040 ## $aSTII-DOST 041 0# $aeng 090 ## $aFil Q149 P5 N25 100 1# $aSevilla-Santos, Patrocinio 100 1# $aLozano, A.M. 100 1# $aSantiago, L. 100 1# $aMendoza, F. 100 1# $aRosario, D. 245 00 $aOxytetracycline production in coconut water$cby Patrocinio Sevilla-Santos, A.M. Lozano, L. Santiago, F. Mendoza and D. Rosario 300 ## $a113-129$bfigures, tables 504 ## $aIncludes bibliographical references 520 3# $aOxytetracycline (OTC) was produced on a: very simple novel medium of coconut water. Buffering and corn steep liquor addition increased the antibiotic content to 145 p,g/ml OTC after 5 days of fermentation. The producer. organism is a local streptomyces isolate NIST S-70-24B. The fermentation brew did not exhibit vitamin B12 activity (E. coli factor). The antibiotic was extracted from the brew and identified as oxytetracycline by comparing its physical and chemical properties with the three tetracyclines. A parallel study on chlortetracycline (CTC) production by Streptomyces aureofaciens NRRL 2209 gave a CTC yield of 0.09 p.g/ml after 72 hours of fermentation and a vitamin B12 activity of 0.14 p,g/mL 650 04 $aScience and technology 650 04 $aOxytetracycline production$xCoconut water 650 04 $aOxytetracycline 650 04 $aFermentation 650 04 $aStreptomyces aureofaciens 650 04 $aTetracyclines 991 ## $wANALYTICS           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC