Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data 001    412265 005    20201212061614.AM 008    201212s |||||||||b ||00||| 040 ## $aDOST-PCHRD 100 1# $aCabanilla, Cristan Q 100 1# $aSeguerra, Cynthia 245 00 $aClinical profile and outcome of pediatric patients with reverse transcription-polymerase chain reaction (RT-PCR)-confirmed influenza A (H1N1) 300 ## $a63-69 504 ## $aRetrospective Studies, Descriptive Studies 520 3# $aBACKGROUND: The World Health Organization declared on June 11, 2009 the first pandemic of the 21st Century caused by the novel Influenza A (H1N1) virus. The virus was observed to be clinically similar to the seasonal influenza, in which case, patients recover even without medical treatment.The virus affected the younger age group even those who are healthy, which make it different from seasonal flu.OBJECTIVE: The study aimed to describe the clinical profile and outcome of pediatric patients with Reverse Transcription-Polymerase Chain Reaction (RT-PCR)-confirmed Influenza A (H1N1).METHODOLOGY: Pediatric patients of the Lung Center of the Philippines seen from May 1 to July 31, 2009 for Influenza-like illness upon presentation and confirmed to have Influenza A (H1N1) virus through Reverse Transcription-Polymerase Chain Reaction (RT-PCR) assay were included in the study. Charts of patients were reviewed. Information from patients was obtained using the WHO Case Summary Form and the National Epidemiology Center Initial Screening of Influenza A (H1N1) form. The patient's demographic data, clinical characteristics, co-morbid conditions, vaccination, clinical course, complications, anti-viral medications received and adverse reactions, and over-all outcome were noted, as well as, exposure to confirmed cases and history of travel.RESULTS: Out of the 243 RT-PCR-confirmed patients, 71.6% (n=174) came from the adolescent age group, with a median age of 13 years old. A predominance of male patients (57.2%) was noted. Fever (92%), cough (83.1%), nasal congestion (52.7%) and sore throat (35%) were the most common presenting signs and symptoms. Bronchial asthma (14.4%) was the leading co-morbidity present and pneumonia was the most common complication. Eight patients (3.3%) were hospitalized during the course of the disease. All RT-PCR-confirmed Influenza A (H1N1) patients recovered and no mortality was noted.CONCLUSIONS: In this study, majority of the RT-PCR-confirmed Influenza A (H1N1) patients were characterized by self-limited, uncomplicated, and febrile respiratory illness, who all recovered with minimal complications. 650 04 $aInfluenza A virus 650 04 $aInfluenza A Virus, H1N1 Subtype 650 04 $avirus diseases 650 04 $aReverse Transcription 650 04 $apolymerase chain reaction 650 04 $art-pcr 650 04 $aReverse Transcriptase Polymerase Chain Reaction 650 04 $ainfluenza a 650 04 $aflu 650 04 $a0-18 years old 650 04 $aassay 650 04 $ainfluenza pandemic 650 04 $aself-limiting 650 04 $aInfluenza A virus 650 04 $aInfluenza A Virus, H1N1 Subtype 650 04 $avirus diseases 650 04 $aReverse Transcription 650 04 $apolymerase chain reaction 991 ## $wANALYTICS           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC