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MARC Record
Bibliographic Data
Control Number
408717
Date and Time of Latest Transaction
20201212061610.AM
General Information
201212s |||||||||b ||00|||
Cataloging Source
DOST-PCHRD
Main Entry - Personal Name
Oblepias, Enrico Gil C
Cristi-Limson, Margaret Joyce A
Title Statement
A rare case of isosexual pseudoprecocious puberty in a patient with mixed germ cell malignancy of the ovary with endodermal sinus tumor and dysgerminoma
Physical Description
166-174
Summary, Etc.
A 4-year old female was admitted to the hospital for evaluation of an abdominal mass. Early appearance of secondary isosexual characteristics such as breast enlargement, axillary and pubic hair, and vaginal bleeding were noted. Pertinent laboratory examination results included a very much elevated serum estradiol, low LH and FSH titers and a negative 24-hour urine hCG. With an identifiable focus in the pelvis that would consolidate the clinical presentation and laboratory findings, our pre-operative diagnosis was: Pseudoprecocious puberty secondary to a functioning ovarian newgrowth probably granulosa cell tumor. The final histopathologic diagnosis unexpectedly was mixed germ cell tumor predominantly yolk sac (endodermal sinus tumor) with areas of dysgerminoma. This is the first locally documented case of ovarian endodermal sinus tumor with the symptomatology of precocity
Subject Added Entry - Topical Term
X
X
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