Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data Control Number 407578 Date and Time of Latest Transaction 20201212061609.AM General Information 201212s |||||||||b ||00||| Cataloging Source DOST-PCHRD Main Entry - Personal Name Moderes, Lagrimas TG   Montes Lao, Ma Luisa   Maranan, Lilia Title Statement An open comparative cross-over study of the combination of clonidine and chlorthalidone (comipres) to determine the efficacy and tolerance as an antihypertensive agent Physical Description 88-91 Summary, Etc. Forty hypertensive patients were given Clonidine-Chlorthalidone for the control of their high blood pressure for a period of four weeks. a wash-off period of at least one week was allowed prior to the drug trial. Statistical analysis of the subsequent blood pressure readings showed that the drug combination, given at twice daily regimen, was effective in lowering both the systolic and diastolic blood pressure even at the start of the study. It was further shown that adequate control of the blood pressure was maintained at a reduced drug schedule of once a day. Minimal side effects consisting of dry mouth, fatigue, nausea, constipation, headaches and dizziness were reported by some of these patients. There was an observed disappearance of said symptoms when the dosage of the medication was reduced. a once-a-day drug schedule has provided significant advantage, since patients compliance became easier to attain Subject Added Entry - Topical Term CROSS-OVER STUDIES, CLONIDINE, CHLORTHALIDONE, ANTIHYPERTENSIVE AGENTS   CROSS-OVER STUDIES, CLONIDINE, CHLORTHALIDONE, ANTIHYPERTENSIVE AGENTS           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC