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MARC Record
Bibliographic Data
Control Number
57884
Date and Time of Latest Transaction
20060619142724.6
General Information
060619s |||||||||b ||00|||
Cataloging Source
PCARRD-DOST
Main Entry - Personal Name
Fernandez, Tomas Jr. J.
Main Entry - Uniform Title
ENGLISH
Title Statement
Anthelmintic principle of local plants
General Note
Baybay, Leyte: VISCA, 1992. 17p
Summary, Etc.
Fresh leaves of ampalaya (Momordica charantia) and ipil-ipil seeds (Leucaena leucocephala) were serially extracted with different solvent systems: Fraction A with chloroform : acetic acid (99:1), B with chloroform : methanol : acetic acid (49.5:49.5:1), C with methanol : water (1:1) and D with hexane extract. These were administered orally to different experimental animals to determine the active principles of local plants having anthelmintic effect. The four fractions (A, B, C and D) contained either of the following components: alkaloids, saponins, flavonoids, anthraquinones, candenolides and tannins. Chromatography test showed that both plants were effective against roundworm in chicken,based on the reduction of eggs per gram feces. The LD50 of Fractions A, B and C revealed that none of the tested bird showed toxic reactions at 600 mg/kg b.w. However, two of the birds that were dosed with Fraction C of ipil-ipil showed difficulty in breathing but recovered two days later. ED50 showed that Fraction A of the two plants has potential anthelminthic activity with increasing dose. However, the percent efficacy of the tested dose is not as good as piperazine
Subject Added Entry - Topical Term
MOMORDICA CHARANTIA
LEUCAENA LEUCOCEPHALA
ANTHELMINTICS
Location
DOST PCARRD
Physical Location
Department of Science and Technology
Philippine Council for Agriculture, Forestry and Natural Resources Research and Development
Digital Copy
Not Available
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