Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data Control Number 407857 Date and Time of Latest Transaction 20201212061609.AM General Information 201212s |||||||||b ||00||| Cataloging Source DOST-PCHRD Main Entry - Personal Name King, Sally Victoria B   Garcia, Robert Dennis J   Manzon, Lou Ver Leigh A Title Statement Haemophilus influenzae type B conjugate vaccine (HiBCV) and heptavalent pneumococcal conjugate vaccine (PCV7) immunization status of patients 5 years and below hospitalized for pneumonia Physical Description 30-36 Summary, Etc. INTRODUCTION: Community-acquired pneumonia remains to be an important cause of morbidity and mortality among the pediatric age group with Streptococcus pneumoniae and Haemophilus influenzae type B being the predominant bacteria identified. Conjugate vaccines against these organisms are available however, the prevalence of pneumonia in our country continues to be high. OBJECTIVES: The aim of this research is to determine the HiBCV and PCV 7 immunization status of children 5 years and below who were hospitalized due to pneumonia compared to controls. This study also aims to describe the clinical outcome of pneumonia among children who were vaccinated with HiBCV and/or PCV7 compared to those without vaccination. METHODS: This retrospective case-control study was conducted in Makati Medical Center from January 1, 2009 to August 31, 2010. Cases were children five years old and below discharged with the final diagnosis of pneumonia. Controls were patients five years and below discharged without pneumonia during the same study period. Medical records were reviewed for information on age, gender, clinical findings upon admission, laboratory results, vaccination status, interventions and outcomes. RESULTS: Two hundred twenty seven charts were reviewed (127 cases and 100 controls). The mean age of patients on admission was 1.9 years (SD ? 1.4). In 98.4% of the cases, chest roentgenograms showed infiltrates. The mean white blood cell count for cases was normal with 11.4 x 103/uL (SD + 6.3). None of the case patients had positive blood culture results. Only 34.6% and 5% of the cases completed age-appropriate doses of HiBCV and PCV7, respectively. No statistical difference was found between the length of hospital stay and duration of antibiotic use and the vaccination coverage for the two vaccines. Children without vaccination coverage had the odds of 1.2-1.3 to develop pneumonia compared to children with at least one dose of either vaccine (HiBCV: OR 1.3, 95% Cl 0.8 to 2.3; PCV7: OR 1.2, 95% CI 0.6 to 2.6). CONCLUSION: The findings indicated that clinical and radiologically-confirmed pneumonia still occurred among children with complete vaccination with HiBCV and PCV7. Although not statistically significant, those without vaccination had higher odds of having pneumonia Subject Added Entry - Topical Term HAEMOPHILUS INFLUENZAE TYPE B   VACCINES, CONJUGATE   HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE   IMMUNIZATION   PNEUMONIA   HAEMOPHILUS INFLUENZAE TYPE B   VACCINES, CONJUGATE   HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE   IMMUNIZATION   PNEUMONIA           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC