Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data Control Number 397207 Date and Time of Latest Transaction 20201212061609.AM General Information 201212s |||||||||b ||00||| Cataloging Source DOST-PCHRD Main Entry - Personal Name Leyesa, Normita D. Title Statement The anti-inflammatory action of the resin extract from the leaves of eggplant Physical Description 153-154 Summary, Etc. This research work was undertaken to determine the usefulness of the anti-inflammatory action of the resin extract from the leave of eggplant to cure inflammation in piles (hemorrhoids). This study could pave the way to seriously consider the anti-inflammatory action of eggplant 9Solanum melongena Linn., Family Solanaceae) that will serve as an answer to the high cost of commercially available medications and somehow contribute to the self-sufficiency program of the government in the use of locally grown medicinal plants. Several laboratory experiments were conducted as part of the investigation. Extraction and purification of the resin extract from the leaves of eggplant after preliminary tests were performed to determine the presence of resins. Findings showed that with the two methods of extraction employed namely, the reflux and continuous extraction using 95 percent ethyl alcohol as solvent, the latter produced a higher yield. The tests conducted on the resin extract such as physical properties, solubility in several solvents and smoke tests verified that the extract is that of resin. The chemical tests performed on the chemical properties of resin. Thin layer chromatography was used to find the number of component present in the resin extract. The functional groups present in the resin extract were determined through the used of the Fourier Transform Infrared (FTIR) Spectrophotometer. The infrared spectrum yielded the following functional groups: alcohols or acids; hydrocarbon skeleton; carbonyl compounds like ketones, aldehydes, carboxylic acids, esters or amides; ketals or acetals. The anti-inflammatory test employed the carrageenin induced edema method on ten male Sprague-Dawley rats. The results showed that at a dose of 250mg., a significant reduction in inflammation was observed. Based on the findings of the study, the researcher recommends the following: a)instill public awareness of the medicinal value, conservation and propagation of eggplant and the continuous investigation and development of its use should be seriously considered; b)resins from the leaves of eggplant may be utilized as a constituents of a pharmaceutical preparation for its anti-inflammatory action; c)toxicity and teratogenicity tests must be conducted on the resin to determine the lowest therapeutic dose; d)determination of the molecular formula by using nuclear magnetic resonance (NMR) should be undertaken and e) further study of the components of the plant and other plant parts aside from the resin must be conducted to obtain other therapeutic actions Subject Added Entry - Topical Term ANTI-INFLAMMATORY AGENTS   SOLANUM MELONGENA   PLANT LEAVES   ANTI-INFLAMMATORY AGENTS   SOLANUM MELONGENA   PLANT LEAVES           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC