Record Details     « New Search       Brief Record Full Record MARC Record     Bibliographic Data Control Number 407865 Date and Time of Latest Transaction 20201212061609.AM General Information 201212s |||||||||b ||00||| Cataloging Source DOST-PCHRD Main Entry - Personal Name Cadorna-Carlos, Josefina   Han, Htay Htay   Bock, Hans L   Gatchalian, Salvacion   Lu-Fong, Margaret   Rogacion, Jossie   Lu-Fong, Margaret   Cordero-Yap, Leticia   Gatchalian, Salvacion Title Statement MMR trivalent vaccine based on safety, reactogenicity and immunogenicity observed in 12-24 month-old healthy Filipino children: Evaluation of lot-to-lot consistency of a live-attenuated measles-mumps-rubella Physical Description 92-96 Summary, Etc. In this double-blind, randomized single-dose study, 194 healthy Filipino children aged 12-24 months were randomized into three groups (1:1:1) to receive one of the three lots of live-attenuated measles-mumps-rubella (MMR) vaccine to assess lot-to-lot consistency in safety and immunogenicity. Adverse events were recorded during 43-day post-vaccination follow-up period. Antibody levels were measured using ELISA pre-vaccination and on Day-60. No statistically significant differences were observed across groups for overall incidences of local and general symptoms (p>0.05) or immune response rates against the three antigens (p=0.835, 0.458 and 0.222 for anti-measles, anti-mumps and anti-rubella, respectively). The three lots demonstrated consistency in their reactogenicity and immunogenicity profile Subject Added Entry - Topical Term MEASLES-MUMPS-RUBELLA VACCINE   ENZYME-LINKED IMMUNOSORBENT ASSAY   PRIORIX   IMMUNOGENICITY   REACTOGENICITY   MEASLES-MUMPS-RUBELLA VACCINE   ENZYME-LINKED IMMUNOSORBENT ASSAY           Physical Location           Digital Copy Not Available          Add to Book Cart  |   Download MARC